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INCRETIN-BASED THERAPIES FDA APPROVED FOR WEIGHT MANAGEMENT The FDA has approved several incretin hormonebased pharmacotherapeutic agents, including liraglutide, semaglutide, dulaglutide, exenatide, lixisenatide, tirzepatide, and orforglipron

Therefore, the current data support its use as a supportive, rather than standalone, biomarkerbest applied as part of a multi-marker panel in clinically challenging cases

Longevity in untreated congenital growth hormone deficiency due to a homozygous mutation in the GHRH receptor gene

Plasma H 2 S shows a negative correlation with obesity, such as waist circumference and waist-to-hip ratio

Ensuring efficacy, safety, and durability comparable to injectable GLP-1 RAs while minimizing adverse effects, particularly gastrointestinal discomfort, is essential

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