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doi: 10.3389/fmolb.2025.1715024 56 ZengYWuYZhangQXiaoX

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Abbreviations MACE: Major adverse cardiovascular event HbA1c: Glycated haemoglobin BMI: Body mass index cHDL: High-density lipoprotein cholesterol cLDL: Low-density lipoprotein cholesterol Tg: Triglycerides HR: Hazard ratio T2D: Type 2 diabetes CAD: Coronary artery disease CVD: Cardiovascular disease ROS: Reactive oxygen species ICD-10-CM: International classification of diseases, 10th revision ATC: Anatomical therapeutic chemical UMAP: Uniform manifold approximation and projection GMM: Gaussian mixture model References Zucatti KP, Teixeira PP, Wayerbacher LF, Piccoli GF, Correia PE, Fonseca NKO, et al

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