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Apart from fisetin and sulforaphane mentioned above, taurine, an endogenous antioxidant, was shown to alleviate OS in diabetic rats by regulating the NF-B and Nrf2/HO-1 signaling cascades

Side Effects & Safety L-carnitine is generally well tolerated in the trial literature

which is systemically transported and serves as a storage form of reduced sulfur, which can be remobilized when needed by plants (Otulak-Kozie et al., 2022a)

doi: 10.1016/j.soard.2020.06.028 108

Taken together, it is clear that there is a need to develop new therapies to prevent insulin resistance which may develop as a consequence of therapeutic SARM use