470 In animal models of Apelin-13-caused cardiomyocyte hypertrophy and heart failure, NCOA4-activated ferritinophagy leads to the upregulation of SFXN1 expression, causing mitochondrial iron overload and mitochondrial ROS overproduction, increased lipid peroxidation, and ultimately, ferroptosis
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It specifies substances and methods prohibited both in- and out-of-competition, as well as those banned in particular sports
Consequently, there is a significant need for alternative sampling methods to support genomic profiling of BM, particularly to inform radiotherapy treatment when surgical resection has not been performed
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