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There is scientific agreement that properly planned and regularly carried out PA (at best daily and outdoors/in nature) seems to act as a preventive measure, delaying or avoiding the onset of certain diseases, and as an effective treatment for subjects already affected by NCDs by increasing the quality of life, slowing down the progression of illness, and/or eradicating it (146151, 158, 159)

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Interestingly, the application of low-magnitude compressive stress (0.03 kPa) on weakly adhesive MDA-MB-231 breast cancer cells decreases their motility, highlighting the critical role of cell-matrix interactions in stress-dependent cell responses [122]