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One common oxidative DNA lesion is 8-hydroxydeoxyguanosine (8-OHdG), which results from the interaction of ROS with guanine bases [97]

Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease

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Despite employing conservative assumptions in this work, the primary source of uncertainty stems from the absence of any formal guidance on the parameterization of these models and validation data, unlike the well-established validation of physiologically based kinetic models against human clinical data (Li et al., 2021

Pharmakeftiki 12(1): 25-31, 1999 37

These factors prove more predictive of mental health outcomes than simple time measurements