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bioRxiv (2025)
InjectCo prescribes GHK-Cu as a physician-supervised compounded topical formulation, which is the route that best fits most skin and hair goals
How glucagon-like peptide 1 receptor agonists work
Our medical directors, Dr
Water Retention (Transient) One of the most common side effects is mild water retention , which typically manifests as: Slight bloating Softness around joints Temporary weight gain due to increased extracellular water This is caused by: Increased GH and IGF-1 levels , which promote sodium retention and water shifts into tissues Water retention is typically: Mild and transient More noticeable at higher doses (300 mcg+) or when stacked with MK-677 (MK-677 (Ibutamoren) Cycle) Managing it: Keep sodium intake moderate Ensure proper hydration Adjust dosing if necessary Increased Appetite Because GHRP-2 binds to the ghrelin receptor , many users experience increased appetite which can be helpful or undesirable depending on your goals
These medications work by mimicking the action of incretin hormones, which are naturally released in response to food intake
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