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GHK-Cu is also available topically at 1 to 3% concentration for localized skin and hair applications

Subdermal application overcomes this barrier and directly reaches the deeper layers of the skin, resulting in higher absorption and efficacy

A 1993 study by Uno and Kurata found that a similar copper-binding peptide (PC1031) increased follicular enlargement when applied to the back skin of fuzzy rats

It does not require proof of efficacy in large trials the way we typically expect from drugs, but it facilitates prescribing, and that changes things a lot, because there wont be a black market anymore

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USA 85 , 72937297 (1988)