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Evaluation of oxidative stress markers in patients with bipolar disorder revealed their increased values in serum and erythrocytes (Akarsu et al

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Because GHK binds Cu(II) tightly, it offers a controlled system for studying how copper may relate to collagen pathways, antioxidant enzyme activity, and gene-expression regulation

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Conversely, SIRT3 overexpression has the opposite effects, 105 suggesting that SIRT3 inhibits AKT-dependent mitochondrial metabolism and EMT, thereby promoting ferroptosis

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