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Though 2- and 4-OHE 2 have similar redox potentials and thus similar redox cycling activity, the greater carcinogenic capacity of 4-OHE 2 can be attributed to its increased reactivity with DNA

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This study aims to investigate whether semaglutide can reduce the progression of noncalcified coronary atherosclerotic plaque volume, as measured by serial coronary computed tomography angiography (CTA), over a one-year period compared to a placebo, in individuals with diabetes