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So by the time a woman reaches her late forties to early fifties

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.McEniery C.M., Yasmin, Hall I.R., Qasem A., Wilkinson I.B., Cockcroft J.R

We also thank other members of the Guertin Lab for helpful discussion

Seven days after a dose, around 44% of that dose's peak remains, and accumulation across weekly doses keeps steady-state levels high enough to stay pharmacologically active throughout the week