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Furthermore, pristine SiO 2 NPs, which could not be taken up by erythrocytes, were shown to promote ROS-mediated and caspase-3-dependent eryptosis [452] (Fig

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Soczynska, J

Therefore, although the apoptosis pathway has been considered an important target for the attenuation of CP-induced AKI for many years, inhibition of apoptosis only could paradoxically sensitize tubular death through necroptosis signaling