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Dysfunction within the CNS Brain imaging studies have demonstrated an association between PDPN and structural changes in key somatosensory regions, such as the thalamus and somatosensory cortex, and altered functional connectivity within ascending pain pathways and cortical regions involved in pain processing

Create a cool, dark sleeping environment and limit screen exposure for at least one hour before bed

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Damage to mitochondrial structure and function can cause abnormal levels and distribution of metal ions, leading to cell dysfunction and even death

miR-122 regulates collagen production via targeting hepatic stellate cells and suppressing P4HA1 expression