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If the stress persists, ATF4 can also promote the transcription of C/EBP homologous protein (CHOP), a pro-apoptotic protein, to induce cell apoptosis (57)

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Signs of Heat Exhaustion and Dehydration: Fatigue and Weakness Dizziness or Lightheadedness Excessive Sweating or Thirst Muscle Cramps If left untreated, heat exhaustion and dehydration can lead to more serious health problems

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