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For a legion of reasons

Since energy costs in a multiple-effect system can be high, larger-capacity systems will typically have more effects to reduce the energy input to the system

If only 0.20.5mg reaches the dermis topically, then direct subcutaneous injection at 0.751.5mg theoretically delivers 37 the bioavailable dose

This conservative approach minimizes copper toxicity risk but may require 16+ weeks to produce observable density changes

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