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Varanasi et al , 2011), suggesting that GLP1R expressed in cells, outside of beta cells, may also have a role in improving glycemic levels even in people who functionally lack beta cells and would ultimately mean lower need for insulin in T1DM patients

However, the optimal dosing strategy remains debated, with some studies suggesting that intermittent high-dose regimens may be less effective or potentially harmful compared to daily dosing

The distinction matters because one requires treatment while the other just requires patience and perhaps slightly adjusted fluid timing

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Understanding weight regain patterns helps with restart timing

For peptides prone to aggregation, add solvent in small increments