glp-1 medication for weight loss How medications are transforming diabetes and treatment 6 Things to Know About

Sitagliptin, a dipeptidyl peptidase-4 inhibitor, was selected as an active-comparator placebo proxy because it was recommended in clinical guidelines as a second-line glucose-lowering therapy, had a similar high cost to the study drugs, showed no effect on cardiovascular outcomes in a large randomized controlled trial and has been validated as a placebo proxy in prior claims-based research 20,41

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McKenna MJ, Zempel JA

PMID 12163482

GLP-1 tells the brain youve had enough, slows how quickly the stomach empties, and dials down the persistent preoccupation with food that many people on these drugs describe disappearing