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Standard dose escalation: 0.25 mg weekly for 4 weeks 0.5 mg weekly for 4+ weeks 1.0 mg weekly for 4+ weeks 1.7 mg weekly if needed 2.4 mg weekly (maximum) There is no requirement to reach 2.4 mg if the patient is responding and tolerating treatment

This schedule gives a UK laboratory a clear window to plan procurement around delivery timelines

Several different brands are available, including Wegovy, Rybelsus and Mounjaro

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In the DFb-treated IVDs, large amounts of regular fibrous tissues were visible with no obvious NP tissue structure or fissures