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Apoptosis is a widely studied mild non-lytic mode of cell death characterized by a decrease in cell volume and fragmentation of the nucleus and involved in many diseases including diabetes [65]

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It is being studied for healing chronic wounds, burns, and surgical incisions, as well as improving post-surgical recovery and reducing scarring

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The 29-gauge needles used for tirzepatide are thin compared to other injectables, yet the longer needle length required for subcutaneous delivery still penetrates multiple tissue layers

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