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However, there is a lack of systematic research on the optimal exercise modality and exercise program to regulate mitophagy, and the specific mechanism of mitophagy to improve metabolic diseases and its exercise intervention has not been fully elucidated

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The receptor proteins predominantly engaged in mitophagy include BNIP3L/NIX, FUNDC1, FKBP8, PHB2, and AMBRA1 (Yao et al., 2021)

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