Since pyrethroids are lipophilic, they tend to bioaccumulate in membranes, where they generate ROS.[] The mitochondrial function is impaired, and the StAR protein is suppressed due to the increased production of ROS.[] One of the StAR protein functions is to shuttle cholesterol from the cytoplasm to the matrix of the mitochondria.[] One limitation in the production of TH is the transfer of cholesterol.[] It has been suggested that pyrethroids inhibit the production of the StAR protein.[] Thus, in the current experiment, reduced TH levels were observed after exposure to CYP, which might have been mediated by the suppression of StAR protein expression
Williams JL, Everett JM, D'Cunha NM, et al
Curr Chem Biol
2004 Mar;134(3):48992
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Bovine, Marine & Vegan Sources Compared (2026) Collagen halal status depends entirely on source: marine collagen from fish is halal, bovine requires zabiha slaughter verification, porcine is haram
