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Prescribers Attempt to Fight Back In response to the recent changes to the bulks lists, some prescribers began encouraging their patients to sign a petition to encourage legislators to make a change and allow some of these substances to be able to be compounded

Published topical skin studies summarized by Schagen included one month of daily thigh application in 20 women, 12-week facial or eye-cream studies in 71 or 41 women, and a 12-week twice-daily Cu-GHK cream study in 67 women [2]

Such studies would also provide more information on its long-term safety and efficacy

While data for topical application is inconclusive, it is advised pregnant women avoid topical application of tretinoin or estriol containing medications

Allergic Reaction: It is long-lasting and worsens over the weeks with continuous use