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The study found no impact on folate levels, but reported a 5% reduction in serum B12 levels when women went from 0 to 30 g of alcohol a day

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The resulting alterations in Phase II drug-metabolizing enzyme activities significantly affect hepatic capacity for detoxification of endogenous and exogenous toxic compounds

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IV hydration isn't a luxury in these cases it's frequently the only clinically viable delivery method for critical nutrients