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It could be observed that ischemia in stroke models causes damage to multiple cells in the brain and blood vessels including neurons, glial cells (astrocytes and microglial cells), and vascular endothelial cells

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HO conceptualized the study and provided expertise

[1] [2] However, longstanding neurological complications, such as peripheral neuropathy or cognitive changes, may require three to six months of consistent treatment before significant improvement occurs, and some damage may be irreversible if treatment is delayed

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