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This study was able to confirm the models biomimetic nature in replicating the in vivo fibrosis, given the embedment of fibroblasts in the hydrogel, which migrated into the clot and led to collagen type I deposition

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The primary outcomes of the study were decreases in SOD activity, IL-1 mRNA, and concentrations of MDA, H 2 O 2 , IL-4, IL-8, and IL-10 in circulation over time

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