If taking the ORAL TABLETS: Do not breastfeed during therapy
doi: 10.1016/j.pharmthera.2013.08.003 128 KamelF.UmbachD
Its active ingredient, tirzepatide, is the first approved GLP-1 and GIP (glucose-dependent insulinotropic polypeptide (GIP) receptor agonist)
Every direct comparison is cross-trial inference
GLP-1s can help you lose weight, but they arent a magic fix
It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)