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Harach T, Pols TW, Nomura M, Maida A, Watanabe M, Auwerx J, Schoonjans K

We review data identifying the roles of key DPP4 substrates in transducing the glucoregulatory, anti-inflammatory, and cardiometabolic actions of DPP4 inhibitors in both preclinical and clinical studies

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Safe exercise involves avoiding temperature extremes and choosing appropriate activities based on age and health status

Additionally, some studies have raised concerns, as ibuprofen treatment can increase the bacterial load and decrease survival in CB6F1 mice following high-dose aerosol infection [130]

MASH , metabolic dysfunction-associated steatohepatitis