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For example, AFM can be used to measure the stiffness of individual muscle fibers or the force generated by single actin-myosin interactions, providing insights into how fatigue impacts muscle function at the molecular level

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For transferrin-bound Mn 3+ , Mn 3+ is released in endosomes and lysosomes, reduced to Mn 2+ , and exported to the cytosol via DMT1 in vitro (Figure 1D)