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The Phase 2 trial showed 22.8% weight loss at this dose

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Under accelerated conditions (40C, 75% relative humidity), the content of this oxidized impurity increases by approximately 0.5% per week

A strong letter of medical necessity should include: your BMI history over at least 12 months, documentation of weight-related comorbidities (hypertension, type 2 diabetes or prediabetes, dyslipidemia, sleep apnea), prior weight-loss attempts and their outcomes, the specific clinical trial data supporting the requested medication, and a statement that the medication is medically necessary (not cosmetic)

The needle tip should be submerged in the liquid