The pi class member GST P1-1 ranks among the least active GSTs with a specific activity of 1.2 mol min 1 mg 1 , which is noteworthy, because this enzyme is present in most tissues 19 (but not in the hepatocytes of the liver 28 )
Microarray and RNA-sequencing studies have mapped its regulatory effect across approximately 4,000 human genes, including upregulation of VEGF, BDNF, and BMP-2 growth factors central to vascular, neural, and bone remodeling respectively
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doi:10.1111/iwj.13490 Fries RB, Wallace WA, Roy S, et al
Stability of a rat model of prehepatic portal hypertension caused by partial ligation of the portal vein
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