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Many users notice initial results, such as reduced appetite or improved blood sugar control, within the first few weeks

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NICE guideline NG145 recommends monitoring TSH every 68 weeks after any change in levothyroxine dose, and then annually once stable

Other possible but uncommon side effects are Acute pancreatitis, cholecystitis, cholelithiasis, anaphylaxis, injection site sensitivity, thrombocytopenia, progression of thyroid cancers if present

However, weight loss varies based on metabolism, diet, and physical activity

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