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In vitro studies also demonstrate that hypoxia, inflammatory, and hyperglycemic conditions further elevate ROS levels, indicating that ROS is a critical factor in disrupting mitochondrial homeostasis [78]
These are two of the most potent chemotherapeutic drugs, but also two of the most damaging to the kidney owing to the oxidative damage and severe inflammation they produce (Launay-Vacher 2008
In aplastic anemia, not only is there a shortage of red blood cells, but there is also a lower-than-normal level of platelets, another type of blood cell
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doi: 10.1016/S0083-6729(05)72005-7
