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It demonstrated protection against H 2 O 2 -induced neurotoxicity in SH-SY5Y cells (a human neuroblastoma cell line) and neuroinflammation in LPS-stimulated BV-2 cells (a microglial cell line)

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GLP-1 receptor agonists have been shown in rodent studies to stimulate C-cell growth in the thyroid, which raised initial concerns about thyroid cancer risk

Potential Risks and Safety Concerns of Stacking Peptides Combining retatrutide with other peptides introduces unpredictable risks including hypoglycaemia, hormonal disruption, elevated IGF-1, cardiovascular effects, and infection from non-sterile self-injection