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Taking these drawbacks into consideration, the prodrugs of EGCG analogs were synthesized with the compounds identified as 2a and 4a having lower susceptibility to be metabolized or inhibited by COMT and having an amplified antiproliferative, antiangiogenic, and antifibrotic effect in HuLM ( Scutellaria barbata D

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Although the overall risk is small, data suggests the highest rates of myocarditis occur after the second dose of the vaccine