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The data showing cagrilintide preferentially reduces fat mass while preserving lean mass is compelling for researchers who care about body composition, not just the scale number
However, as seen in patient Pem010 (Supplementary Table S1 and Supplementary Fig
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Cagrilintide doesnt touch GLP-1 at allit works through amylin and calcitonin receptors, which is a fundamentally different hormonal route
We dont want to offer the same treatment for everyone, because what works well for one patient may not work for another
Researchers studying the emerging field of triple agonism and glucagon's role in metabolic regulation may prefer retatrutide, the most novel compound of the three
