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Baumholtz says
The invention is further illustrated by the following examples: EXAMPLE 1 preparation of Merrifield Resin and 1- (2-hydroxyethyl) imidazole solid phase Supports Weighing 120mmol of 1- (2-hydroxyethyl) imidazole, dissolving in tetrahydrofuran, dropwise adding a proper amount of concentrated sulfuric acid, adding 180mmol of liquid isobutene under an ice bath condition, stirring overnight at normal temperature, extracting, and crystallizing to obtain the tert-butyl protected hydroxyl 1- (2-hydroxyethyl) imidazole (compound 1)
It is contraindicated in patients with known hypersensitivity to semaglutide or any other components of this product
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L., Carithers, R
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