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In addition to , and cells in the pancreas, the receptor has been found in a variety of other tissues, including the intestine, stomach, lungs, heart, kidneys and several regions of the central nervous system (Holst et al., 2019

30 Keliher et al ran a series of modifications of Lys 12 in exenatide, indicating that this position is not important for interactions with GLP-1R and that it is, to some extent, tolerant of bigger groups