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Some studies have even suggested that the act of injecting filler can stimulate collagen to a small degree, so you can benefit from both skin rejuvenation and wrinkle reduction with an injectable treatment

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It promotes cell differentiation and proliferation, protein synthesis and muscle growth

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A volume of 350 L of 0.1 M potassium phosphate buffer (pH 7.4), 50 L of 1 mM substrate (diclofenac for CYP2C9 assay and dextromethorphan for CYP2D6, both substrates purchased from Sigma-Aldrich, USA) and 50 L of 2.5 mg/mL microsome (obtained from rat livers from respective groups) were mixed separately in Eppendorf tubes