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It was hypothesized that riboflavin might be involved in the nonenzymatic reduction of weakly soluble Fe 3+ to Fe 2+ due to the use of mechanisms for iron assimilation, distinguished from most flavinogenic yeasts that do not overproduce riboflavin under conditions of iron limitation (Vasileva et al

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The positioning of this CDK11 segment (residues 751762) coincides with substrate peptides visualised in other CDK structures 36,42 and thus precludes substrate access to the active site (Fig

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doi: 10.1038/nri.2016.117 272 NewtonAHCardaniABracialeTJ