asa guidelines for glp 1 drugs 2025 ADS/ANZCA/GESA/NACOS clinical practice recommendations on the peri-procedural use of GLP-1/GIP receptor agonists Your patient took semaglutide this

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Conclusions The development of semaglutide from an engineered GLP-1 analogue in the laboratory to a globally approved, first-line therapy for diabetes and obesity illustrates the power of modern translational pharmacology

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In contrast, the delayed phase involves transcriptional upregulation and synthesis of cytoprotective proteins, such as superoxide dismutase, heat shock proteins, and inducible nitric oxide synthase, along with modulation of anti-apoptotic pathways

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These risks are minimized by pausing blood thinners when appropriate, using sterile technique, and guiding the needle with fluoroscopy