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September 4, 2025

The human Hb (mu) class glutathione S-transferases are encoded by a dispersed gene family

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Then, the membranes were incubated overnight at 4 C with primary antibodies, followed by washing with Tris-buffered saline with Tween-20 (TBST)

Finally, as a proof-of-concept study, we bioisosterically replace the naphthyl ring of utrophin modulator ezutromid, with a range of aryl-fused BCHeps, and demonstrate the retainment of bioactivity while improving metabolic stability to CYP enzymes

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