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Its approved status is reflected in the ChEMBL registry at maximum phase 4

this model is static PES improves separation but remains a single perturbation snapshot MEA captures correlates of state transitions, not full continuous dynamics This paper shows local cortical dynamics only (not whole-brain physiology) so results are: developmental-stage dependent model-specific (2D organoid in vivo brain) perturbation-dependent Why fully dynamic modeling is nearly impossible

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Trusolino L, Bertotti A, Comoglio PM

The compound acts on nitric oxide synthesis pathways, playing a direct role in regulating vascular inflammation and tissue swelling