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The particles were extracted on a binned dataset with a pixel size of 2.142 and were subjected to reference-free 2D classification, producing 4,334,371 particles with well-defined averages

Mechanism of Action: an isotopic deuterated isomer of tetrabenazine, where two O-linked methyl groups (O-CH 3 ) of the tetrabenazine molecule have been replaced by 2 trideuteromethyl groups (O-CD 3 )

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