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Complex dosing schedules : These protocols require meticulous monitoring and documentation, adding to the workload and operational costs

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Geographical location affects costs, with London and South East England generally commanding higher prices than other UK regions

Bidirectional interactions with Bifidobacterium and Lactobacillus suggest that dysbiosis may impair MI bioavailability, exacerbating IR and androgen excess (235)

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Failing to use backup contraception when needed can increase the risk of unintended pregnancy