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DOI 10.1111/dom.14725 - about two-thirds regain within a year

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Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine

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Furthermore, most available studies are of short duration and lack long-term follow-up to assess whether repeated or chronic IF leads to sustained alterations in thyroid function or clinically meaningful hypothyroidism [60] (Table 2)