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The odds of achieving 10%, 15%, and 20% or more weight loss were significantly higher with semaglutide (70.9%, 55.6%, and 38.5%, respectively) compared to liraglutide (25.6%, 12.0%, and 6.0%)

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Certain combinations of symptoms, such as painless jaundice or persistent upper abdominal pain with weight loss, may prompt urgent referral under NICE suspected cancer guidelines (NG12)