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Side effects observed in Phase 2 studies include nausea, vomiting, diarrhoea, decreased appetite, and injection-site reactions

Fat gain should not happen if you're in a deficit

Tirzepatide is administered once weekly via subcutaneous injection, with doses starting at 2.5 mg for a 4-week initiation period, then titrating every 4 weeks up to a maximum of 15 mg

Another limitation is that we did not directly measure body length of wild-type and MC4R KO mice

In contrast, white adipose tissues store excess fat and decrease energy expenditure

Dose adjustments are typically based on response, tolerance, and overall treatment goals