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Whether theyve stopped losing weight, they have very severe side effects, whatever the reason is, were calling it a failure, and theres patients who are taking these drugs and theyre getting stuck on it

However, these drugs are known to cause a plethora of adverse effects such as weight gain, edema, intestinal discomfort and hypoglycemia (2)

Endocrinology 154: 4-8, 2013

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Your provider will guide the transition, typically starting Zepbound at a lower dose even if youre on high-dose Wegovy, then gradually increasing

In my case, my resting heart rate went from around 40 beats per minute to about 65