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Its resistance to degradation, combined with careful handling and storage, supports its continued investigation in preclinical studies of tissue repair, blood vessel formation, and gene expression

Also, the concomitant use of topiramate with any other drug producing metabolic acidosis, or potentially in patients on a ketogenic diet, may create a physiological environment that increases the risk of kidney stone formation, and should therefore be avoided

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It also wastes more energy as heat, reducing the actual usable power for your device

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COTI-2, a novel small molecule that is active against multiple human cancer cell lines in vitro and in vivo