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L-carnitine supplementation is generally safe at doses of 2 grams or less per day, though mild side effects are possible

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This approach is especially valuable for patients whose genetic test results indicate heightened GLP1R sensitivity or those with a history of digestive issues

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This can stem from the caloric deficit itself, from the metabolic adjustments the body is making, or from dehydration if fluid intake has not increased to compensate for the dietary changes